Electron spin resonance studies on the spin label of rat cardiac mitochondria treated with adriamycin.
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Electron spin resonance studies on the spin label of rat cardiac mitochondria treated with adriamycin.
Adriamycin (ADR), which is a potent antitumor agent, has severe cardiotoxicity; however, the underlying mechanism is not well understood. In our present study, the electron spin resonance (ESR) technique was employed to analyze the physical properties of cardiac mitochondrial membrane treated with ADR. After intercalcation of spin probe into the isolated cardiac mitochondrial membrane, mitochon...
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the magnetisation and electron spin resonance (esr) spectrum of two specimens of tetrahedral amorphous carbon (ta-c), deposited from a filtered cathodic arc, were measured over a wide temperature range. the magnetisation was found to consist of superparamagnetic, paramagnetic and diamagnetic contributions. the superparamagnetic contribution resembled that recently found in carbon prepared from ...
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Rats were given i.p. injections of Adriamycin (4 mg/kg body weight) for 6 consecutive days. Electron spin resonance spectrometry with spin labeling and a trapping technique was applied to heart mitochondria obtained from treated and control animals, in order to examine the physical response of heart mitochondrial membrane affected by Adriamycin. The Adriamycin treatment resulted in a decrease o...
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ژورنال
عنوان ژورنال: The Kurume Medical Journal
سال: 1987
ISSN: 0023-5679,1881-2090
DOI: 10.2739/kurumemedj.34.59